Mindfulness Intervention to Study the Neurobiology of Depression (MIND)

Mindfulness was taught to teenagers with a history of depression as one strategy for being aware of maladaptive thinking patterns such as rumination. Mindfulness was also taught as an alternative to “getting stuck in your head”. Teenagers who received 8 weeks of this intervention, experienced a reduction in residual depression symptoms compared to teenagers who …

Mechanisms of mindfulness and stress resilience: A mobile app mindfulness training study

Thousands of studies show that mindfulness interventions improve cognitive, affective, stress, and health outcomes, but very little experimental work attempts to explain the mechanisms underlying this broad range of effects. This study uses a novel smartphone training paradigm to experimentally dismantle the components of mindfulness training and test their effects on affective and stress outcomes. …

Does meditation cause pain relief through endogenous opioids?

There is growing evidence that meditation practice can reduce the experience of pain. However, what is going on in the brain during meditation that causes this pain relief has been a mystery. We guessed that meditation might reduce pain by releasing natural brain chemicals called endogenous opioids. Endogenous opioids reduce pain via the same brain …

Examining the relationship of meditation experience to the neural correlates of spontaneous emotion regulation

Training in mindfulness meditation has been associated with more adaptive emotional and behavioral responding, as indicated by reductions in symptoms of a range of clinical disorders, increased psychological well-being in non-clinical populations, and reduced mind-wandering. Despite compelling evidence for a relationship between meditation and mental health, the mechanisms responsible for its salutary effects are largely …

The role of endogenous opioidergic systems in mindfulness meditation-related pain relief

Endogenous opioids have been repeatedly shown to be involved in the cognitive inhibition of pain. Mindfulness meditation, a practice premised on directing nonjudgmental attention to arising sensory events, reduces pain by engaging mechanisms supporting the cognitive control of pain. However, it was unknown if mindfulness-meditation-based analgesia is mediated by opioids, an important consideration for using …

Exploring the impact of a mindfulness intervention on adolescents’ self-compassion and emotional well-being

As adolescents struggle with the multitude of physiological and socioemotional changes taking place during this developmental period, the goal of this study was to implement a mindfulness program for teens and measure both self-report assessments of emotional well-being (perceived stress, life satisfaction, positive and negative affect) and physiological responses to a laboratory social stressor (heart …

Effects of yogic breathing on sleep and well-being in college students: Exploration of psychophysiological mechanisms

Insomnia is a prevalent health concern in older adults with numerous adverse consequences. Prior research suggests that the sleep disturbance and related complaints are driven by physiological hyperarousal and deficiencies in the autonomic nervous system, particularly parasympathetic activity, that inhibit healthy sleep-wake regulation. Pharmacological treatments are not viable long-term, and current behavioral and contemplative interventions …

A longitudinal training study to delineate the specific causal effects of open monitoring versus focused attention techniques on emotional regulation skills

Difficulties with emotion regulation could be a core mechanism of mood and anxiety disorders. Various meditation-based interventions are found to ameliorate a wide range of psychological problems however, it is crucial to understand how different types of meditation improve emotional abilities to develop structured treatment and preventative protocols for emotional disorders. Based on a commonly …